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Lipin 1 Antibody

Lipin 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLipin 1 Primary Polyclonal Antibody
Also known asLipin 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLipin 1
SpecificityThis is a highly specific antibody against Lipin 1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lipin 1
Gene ID number23175
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism, LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels, LPIN1 selectively activates a subset of PGC1 alpha target pathways, Lipin 2 and Lipin 3, This family contains three members: Lipin 1, a heterogeneous group of disorders characterized by loss of body fat, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain, all of which contain a nuclear signal sequence, fatty liver, hypertriglyceridemia and insulin resistance, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha, resulting in insulin resistance and lipodystrophy, whereas a deficiency in LPIN1 may deter normal adipose tissue development, Lipin 1 is a member of the Lipin family of nuclear proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LPIN1, LPIN1_HUMAN, PAP1, Phosphatidate phosphatase LPIN1, KIAA0188
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLipin 1
Short nameLipin 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLipin 1 (Antibody to)
Alternative techniqueantibodies
Identity 13345
Gene LPIN1
Long gene name lipin 1
Synonyms KIAA0188
Locus 2p25, 1
Discovery year 2001-01-24
GenBank acession D80010
Entrez gene record 23175
Pubmed identfication 11138012 8724849 16950137
RefSeq identity NM_145693
Classification Lipins
Havana BLAST/BLAT OTTHUMG00000119082

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