Name : Lipin 1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4729961844
| Long name | Biotin Conjugated, Lipin 1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Lipin 1 |
| Specificity | This is a highly specific antibody against Lipin 1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human Lipin 1 |
| Gene ID number | 23175 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Rat, Mouse |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism, LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels, LPIN1 selectively activates a subset of PGC1 alpha target pathways, Lipin 2 and Lipin 3, This family contains three members: Lipin 1, a heterogeneous group of disorders characterized by loss of body fat, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain, all of which contain a nuclear signal sequence, fatty liver, hypertriglyceridemia and insulin resistance, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha, resulting in insulin resistance and lipodystrophy, whereas a deficiency in LPIN1 may deter normal adipose tissue development, Lipin 1 is a member of the Lipin family of nuclear proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | LPIN1, LPIN1_HUMAN, PAP1, Phosphatidate phosphatase LPIN1, KIAA0188 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Lipin 1 Conjugated |
| Short name | Conjugated, Lipin 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, Lipin 1 (Antibody to) |
| Alternative technique | antibodies |