Name : Lipocalin 2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6558384546
| Long name | Lipocalin 2 Primary Polyclonal Antibody |
| Also known as | Lipocalin 2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Lipocalin 2 |
| Specificity | This is a highly specific antibody against Lipocalin 2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 147-166/198 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lipocalin 2 |
| Gene ID number | 3934 |
| Swiss Prot | P80188 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds iron through association with 2, In contrast, Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, Involved in innate immunity, Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, depending on the context, inducing expression of the proapoptotic protein BCL2L11/BIM, innate immunity and renal development, iron chelation and iron transfer to the extracellular medium, leading to limit bacterial growth, leading to release of iron and subsequent increase of intracellular iron concentration, possibly by sequestrating iron, resulting in apoptosis, thereby reducing intracellular iron concentration, while iron-free form decreases intracellular iron levels, 5-DHBA), 5-dihydroxybenzoic acid (2, Iron-trafficking protein involved in multiple processes such as apoptosis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 25 kDa alpha-2-microglobulin-related subunit of MMP-9, HNL, LCN2, Lipocalin-2, MSFI, NGAL, Neutrophil gelatinase-associated lipocalin, Oncogene 24p3, Siderocalin LCN2, p25, 24p3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Lipocalin 2 |
| Short name | Lipocalin 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Lipocalin 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6526 |
| Gene | LCN2 |
| Long gene name | lipocalin 2 |
| Synonyms gene name | lipocalin 2 (oncogene 24p3) |
| Synonyms | NGAL 24p3 |
| Synonyms name | oncogene 24p3 neutrophil gelatinase-associated lipocalin siderocalin |
| Locus | 9q34, 11 |
| Discovery year | 1994-04-29 |
| Entrez gene record | 3934 |
| Pubmed identfication | 7683678 |
| RefSeq identity | NM_005564 |
| Classification | Lipocalins |
| Havana BLAST/BLAT | OTTHUMG00000020734 |