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LIS1 Antibody, ALEXA FLUOR 350

LIS1 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, LIS1 Polyclonal Antibody
Also known asAnti-LIS1 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLIS1
SpecificityThis is a highly specific antibody against LIS1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LIS1
Gene ID Number5048
Swiss ProtP43034
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules, May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing, May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end, Neuronal migration involves a process called nucleokinesis, Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity), Positively regulates the activity of the minus-end directed microtubule motor protein dynein, Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate, Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates, Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms LIS1 PAFAH NudF
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetLIS1
Short nameLIS1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, LIS1 (Antibody to)
Alternative techniqueantibodies
Identity 8574
Gene PAFAH1B1
Long gene name platelet activating factor acetylhydrolase 1b regulatory subunit 1
Synonyms gene MDCR MDS
Synonyms gene name alpha subunit (45kD) Miller-Dieker syndrome chromosome region platelet-activating factor acetylhydrolase, alpha subunit 45kDa platelet-activating factor acetylhydrolase, isoform Ib, isoform Ib, isoform Ib, platelet-activating factor acetylhydrolase, regulatory subunit 1 (45kDa) , subunit 1 (45kDa) platelet-activating factor acetylhydrolase 1b
Synonyms name lissencephaly-1
Locus 17p13, 3
Discovery year 1998-04-03
GenBank acession L25107
Entrez gene record 5048
Pubmed identfication 8355785 9063735
RefSeq identity NM_000430
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000177574

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