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LIS1 Antibody, Cy5 Conjugated

LIS1 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, LIS1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLIS1
SpecificityThis is a highly specific antibody against LIS1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LIS1
Gene ID number5048
Swiss ProtP43034
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules, May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing, May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end, Neuronal migration involves a process called nucleokinesis, Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity), Positively regulates the activity of the minus-end directed microtubule motor protein dynein, Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate, Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates, Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms LIS1 PAFAH NudF
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetLIS1 Conjugated
Short name Conjugated, LIS1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, LIS1 (Antibody to)
Alternative techniqueantibodies
Identity 8574
Gene PAFAH1B1
Long gene name platelet activating factor acetylhydrolase 1b regulatory subunit 1
Synonyms gene MDCR MDS
Synonyms gene name alpha subunit (45kD) Miller-Dieker syndrome chromosome region platelet-activating factor acetylhydrolase, alpha subunit 45kDa platelet-activating factor acetylhydrolase, isoform Ib, isoform Ib, isoform Ib, platelet-activating factor acetylhydrolase, regulatory subunit 1 (45kDa) , subunit 1 (45kDa) platelet-activating factor acetylhydrolase 1b
Synonyms name lissencephaly-1
Locus 17p13, 3
Discovery year 1998-04-03
GenBank acession L25107
Entrez gene record 5048
Pubmed identfication 8355785 9063735
RefSeq identity NM_000430
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000177574

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