Filters

Livin Antibody, ALEXA FLUOR 350

Livin Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Livin Polyclonal Antibody
Also known asAnti-Livin PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLivin
SpecificityThis is a highly specific antibody against Livin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range100-150/298
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Livin
Gene ID Number79444
Swiss ProtQ96CA5
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen As it is a weak caspase inhibitor, CASP7 and CASP9, In vitro, Isoform 1 blocks staurosporine-induced apoptosis, Isoform 2 blocks etoposide-induced apoptosis, Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing, Its anti-apoptotic activity is mediated through the inhibition of CASP3, May contribute to caspase inhibition, Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, Suppression of apoptosis is mediated by activation of MAPK8/JNK1, This activation depends on TAB1 and NR2C2/TAK1, and cell cycle control, and possibly also of MAPK9/JNK2, as well as by its E3 ubiquitin-protein ligase activity, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions, cell proliferation, etoposide or staurosporine, inhibits CASP3 and proteolytic activation of pro-CASP9, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival, Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms mliap ML-IAP KIAP RNF50
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetLivin
Short nameLivin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Livin (Antibody to)
Alternative techniqueantibodies
Identity 13702
Gene BIRC7
Long gene name baculoviral IAP repeat containing 7
Synonyms gene name baculoviral IAP repeat-containing 7
Synonyms name melanoma inhibitor of apoptosis protein kidney inhibitor of apoptosis protein livin inhibitor-of-apoptosis livin
Locus 20q13, 33
Discovery year 2001-03-06
GenBank acession AF301009
Entrez gene record 79444
Pubmed identfication 11024045 11162435
RefSeq identity NM_139317
Classification Baculoviral IAP repeat containing Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000032957

Similar products

Subscribe to our Newsletter