Name : LLGL1 + LLGL2(Ser650+Ser654) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN6555264951
| Long name | LLGL1 + LLGL2(Ser650+Ser654) Antibody |
| Also known as | LLGL1 + LLGL2(Ser650+Ser654) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LLGL1 + LLGL2 Ser650+Ser654 |
| Specificity | This is a highly specific antibody against LLGL1 + LLGL2 Ser650+Ser654 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser650+Ser654 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654 |
| Gene ID number | 3996 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In fly, In human, LLGL2 is a protein similar to lethal giant larvae of Drosophila, The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17, The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC), this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells, LLGL1 is a protein that is similar to a tumor suppressor in Drosophila |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DLG4, HGL, HUGL, HUGL1, L2GL1_HUMAN, L2GL2_HUMAN, LGL2, LLGL, LLGL1 + LLGL2 phospho Ser650 + Ser654, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, lethal giant larvae homolog 1, lethal giant larvae homolog 2, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 Ser650/654, LLGL1 + LLGL2 phospho S650 + S654 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LLGL1 + LLGL2(Ser650+Ser654) |
| Short name | LLGL1 + LLGL2(Ser650+Ser654) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | lethal giant larvae homolog 1 (Drosophila) and lethal giant larvae homolog 2 (Drosophila)(Ser650+Ser654) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, Cytoplasm, Cytoplasm, DLG4 and HUGL and HUGL-1 and HUGL1 and LLGL, HGL and LGL2, LLGL1 and IDBG-33645 and ENSG00000131899 and 3996, LLGL1 and IDBG-638036 and ENSBTAG00000004635 and 781865, LLGL2 and IDBG-68503 and ENSG00000073350 and 3993, Llgl1 and IDBG-181336 and ENSMUSG00000020536 and 16897, Llgl2 and IDBG-214360 and ENSMUSG00000020782 and 217325, PDZ domain binding, lethal giant larvae homolog 2 (Drosophila), protein kinase binding, this GO :0000137 and this GO lgi cis cisterna and cellular component this GO :0000139 and this GO lgi membrane and cellular component this GO :0005097 and Rab GTPase activator activity and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006887 and exocytosis and biological process this GO :0006893 and this GO lgi to plasma membrane transport and biological process this GO :0007409 and axonogenesis and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030424 and axon and cellular component this GO :0030864 and cortical actin cytoskeleton and cellular component this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031901 and early endosome membrane and cellular component this GO :0032588 and trans- this GO lgi network membrane and cellular component this GO :0032851 and positive regulation of Rab GTPase activity and biological process this GO :0035090 and maintenance of apical/basal cell polarity and biological process this GO :0035748 and myelin sheath abaxonal region and cellular component, this GO :0005097: Rab GTPase activator activity, this GO :0005097: Rab GTPase activator activity and also this GO :0005198: structural molecule activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005198: structural molecule activity, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006887 and exocytosis and biological process this GO :0007049 and cell cycle and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0032878 and regulation of establishment or maintenance of cell polarity and biological process this GO :0051301 and cell division and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0030165: PDZ domain binding, this GO :0019901: protein kinase binding, this GO :0030165: PDZ domain binding, 52154 and IDBG-643198 and ENSBTAG00000020067 and 539545, lethal giant larvae homolog 1 (Drosophila) |
| Identity | 6629 |
| Gene | LLGL2 |
| Long gene name | LLGL2, scribble cell polarity complex component |
| Synonyms gene name | lethal giant larvae homolog 2 (Drosophila) lethal giant larvae homolog 2, scribble cell polarity complex component |
| Synonyms | HGL Hugl-2 |
| Locus | 17q25, 1 |
| Discovery year | 1997-01-28 |
| GenBank acession | X87342 |
| Entrez gene record | 3993 |
| Pubmed identfication | 22580609 |
| RefSeq identity | NM_004524 |
| Classification | Scribble complex WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000179685 |