LOX 1 Antibody, Biotin Conjugated

LOX 1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, LOX 1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	LOX 1
Specificity	This is a highly specific antibody against LOX 1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	224-274/274
Subcellular location	Extracellular
Source	KLH conjugated synthetic peptide derived from Rabbit LOX-1
Gene ID number	100009322
Swiss Prot	Q9XTA8
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Also acts as a receptor for advanced glycation end (AGE) products, Also involved in inflammatory process, In addition to binding oxLDL, Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, activated platelets, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity), by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, monocyte adhesion and apoptosis, monocytes, pro-oxidative conditions and apoptosis, resulting in pro-inflammatory responses, thereby participating in cell-mediated antigen cross-presentation, Receptor that mediates the recognition
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	LOX 1 Conjugated
Short name	Conjugated, LOX 1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, LOX 1 (Antibody to)
Alternative technique	antibodies
Identity	6664
Gene	LOX
Long gene name	lysyl oxidase
Locus	5q23, 1
Discovery year	1986-01-01
Entrez gene record	4015
Pubmed identfication	1685472
Havana BLAST/BLAT	OTTHUMG00000128914
Locus Specific Databases	ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

LOX 1 Antibody, Biotin Conjugated

LOX 1 Antibody, Biotin Conjugated size: 0.1ml 333

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