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LOX 1 Antibody, Cy7 Conjugated

LOX 1 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, LOX 1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLOX 1
SpecificityThis is a highly specific antibody against LOX 1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range224-274/274
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from Rabbit LOX-1
Gene ID number100009322
Swiss ProtQ9XTA8
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also acts as a receptor for advanced glycation end (AGE) products, Also involved in inflammatory process, In addition to binding oxLDL, Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, activated platelets, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity), by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, monocyte adhesion and apoptosis, monocytes, pro-oxidative conditions and apoptosis, resulting in pro-inflammatory responses, thereby participating in cell-mediated antigen cross-presentation, Receptor that mediates the recognition
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetLOX 1 Conjugated
Short name Conjugated, LOX 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, LOX 1 (Antibody to)
Alternative techniqueantibodies
Identity 6664
Gene LOX
Long gene name lysyl oxidase
Locus 5q23, 1
Discovery year 1986-01-01
Entrez gene record 4015
Pubmed identfication 1685472
Havana BLAST/BLAT OTTHUMG00000128914
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

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