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LRP5L Antibody

LRP5L Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLRP5L Primary Polyclonal Antibody
Also known asLRP5L PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLRP5L
SpecificityThis is a highly specific antibody against LRP5L
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRP5L
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen However, LRP is expressed in rat tibia, LRP5 affects bone mass accrual during growth, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family, LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway, LRP5 is most closely related to LRP1, LRP5L is a related protein that exists as two isoforms produced by alternative splicing, LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG), Of the known family members, VLDLR (very low density lipoprotein receptor) and ApoER2, YWTD repeats and an O-linked sugar domain, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, including LDLR (low density lipo-protein receptor), specifically in areas of the bone that are involved in remodeling, Members of the LDL receptor gene family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GP330, LRP-5-like, LRP5L, LRP5L_HUMAN, Low-density lipoprotein receptor-related protein 5-like protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLRP5L
Short nameLRP5L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namelow density lipoprotein receptor-related protein 5-like (Antibody to)
Alternative techniqueantibodies
Alternative to gene target LRP5L and IDBG-3018 and ENSG00000100068 and 91355, Wnt-activated receptor activity, multiple, this GO :0017147 and Wnt-protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process, this GO :0017147: Wnt-protein binding, this GO :0017147: Wnt-protein binding and also this GO :0042813: Wnt-activated receptor activity, this GO :0042813: Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5-like
Identity 25323
Gene LRP5L
Long gene name LDL receptor related protein 5 like
Synonyms gene name low density lipoprotein receptor-related protein 5-like
Synonyms DKFZp434O0213
Locus 22q11, 23
Discovery year 2005-10-09
GenBank acession AL137651
Entrez gene record 91355
RefSeq identity NM_182492
Havana BLAST/BLAT OTTHUMG00000150900

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