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LRP5L Antibody, FITC Conjugated

LRP5L Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, LRP5L Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLRP5L
SpecificityThis is a highly specific antibody against LRP5L
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LRP5L
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background However, LRP is expressed in rat tibia, LRP5 affects bone mass accrual during growth, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family, LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway, LRP5 is most closely related to LRP1, LRP5L is a related protein that exists as two isoforms produced by alternative splicing, LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG), Of the known family members, VLDLR (very low density lipoprotein receptor) and ApoER2, YWTD repeats and an O-linked sugar domain, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, including LDLR (low density lipo-protein receptor), specifically in areas of the bone that are involved in remodeling, Members of the LDL receptor gene family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms DKFZp434O0213
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetLRP5L Conjugated
Short name FITC Conjugated, LRP5L Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, low density lipoprotein receptor-related protein 5-like (Antibody to)
Alternative techniqueantibodies
Alternative to gene target LRP5L and IDBG-3018 and ENSG00000100068 and 91355, Wnt-activated receptor activity, multiple, this GO :0017147 and Wnt-protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process, this GO :0017147: Wnt-protein binding, this GO :0017147: Wnt-protein binding and also this GO :0042813: Wnt-activated receptor activity, this GO :0042813: Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5-like
Identity 25323
Gene LRP5L
Long gene name LDL receptor related protein 5 like
Synonyms gene name low density lipoprotein receptor-related protein 5-like
Locus 22q11, 23
Discovery year 2005-10-09
GenBank acession AL137651
Entrez gene record 91355
RefSeq identity NM_182492
Havana BLAST/BLAT OTTHUMG00000150900

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