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LRRFIP1 Antibody

LRRFIP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLRRFIP1 Primary Polyclonal Antibody
Also known asLRRFIP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLRRFIP1
SpecificityThis is a highly specific antibody against LRRFIP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRRFIP1
Gene ID number9208
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Flightless I has a C-terminal TaR-like domain which binds Actin and therefore the association of LRRFIP1 with the LRR of Flightless I may provide a link between the Actin cytoskeleton and RNA in mammalian cells, In contrast, LRRFIP1 binds double-stranded RNA with high affinity, LRRFIP1 does not bind single-stranded DNA or RNA significantly and binds double-stranded DNA weakly, LRRFIP1 is also believed to control smooth muscle cell proliferation following arterial injury through PDGF-A repression, The N-terminus of LRRFIP1 shows high homology to the coiled-coil domain of FLAP, The RNA binding domain has been identified and encompasses a lysine-rich motif, a protein which binds the leucine-rich repeat (LRR) of Flightless I, and the interaction of LRRFIP1 with the LRR of Flightless I has been confirmed, and two molecules of LRRFIP1 bind the TaR stem, LRRFIP1 is an 738 amino acid human protein whose rodent counterpart is known as Lrrfip1 (also designated FLAP in mouse)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLAP1, FLIIAP 1, FLIIAP1, GC binding factor 2, GC-binding factor 2, GCF 2, GCF2, HUFI 1, HUFI1, LRR FLII interacting protein 1, LRR FLII-interacting protein 1, LRRF1_HUMAN, LRRFIP 1, Leucine rich repeat flightless interacting protein 1, Leucine rich repeat in FLII interacting protein 1, Leucine-rich repeat flightless-interacting protein 1, Lrrfip1, MGC10947, MGC119738, MGC119739, NEDD8 conjugating enzyme, TAR RNA interacting protein, TAR RNA-interacting protein, TRIP, Transcription factor 9 like, FLAP 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLRRFIP1
Short nameLRRFIP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLRRFIP1 (Antibody to)
Alternative techniqueantibodies
Identity 6702
Gene LRRFIP1
Long gene name LRR binding FLII interacting protein 1
Synonyms gene name leucine rich repeat (in FLII) interacting protein 1
Synonyms FLAP-1 FLIIAP1 TRIP GCF-2 HUFI-1
Synonyms name GC-binding factor 2
Locus 2q37, 3
Discovery year 1999-02-15
GenBank acession AJ223075
Entrez gene record 9208
Pubmed identfication 9705290 9525888 16199883
RefSeq identity NM_004735
Havana BLAST/BLAT OTTHUMG00000133339

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