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LRRFIP1 Antibody, FITC Conjugated

LRRFIP1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, LRRFIP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLRRFIP1
SpecificityThis is a highly specific antibody against LRRFIP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LRRFIP1
Gene ID number9208
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Flightless I has a C-terminal TaR-like domain which binds Actin and therefore the association of LRRFIP1 with the LRR of Flightless I may provide a link between the Actin cytoskeleton and RNA in mammalian cells, In contrast, LRRFIP1 binds double-stranded RNA with high affinity, LRRFIP1 does not bind single-stranded DNA or RNA significantly and binds double-stranded DNA weakly, LRRFIP1 is also believed to control smooth muscle cell proliferation following arterial injury through PDGF-A repression, The N-terminus of LRRFIP1 shows high homology to the coiled-coil domain of FLAP, The RNA binding domain has been identified and encompasses a lysine-rich motif, a protein which binds the leucine-rich repeat (LRR) of Flightless I, and the interaction of LRRFIP1 with the LRR of Flightless I has been confirmed, and two molecules of LRRFIP1 bind the TaR stem, LRRFIP1 is an 738 amino acid human protein whose rodent counterpart is known as Lrrfip1 (also designated FLAP in mouse)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLAP-1 FLIIAP1 TRIP GCF-2 HUFI-1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetLRRFIP1 Conjugated
Short name FITC Conjugated, LRRFIP1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, LRRFIP1 (Antibody to)
Alternative techniqueantibodies
Identity 6702
Gene LRRFIP1
Long gene name LRR binding FLII interacting protein 1
Synonyms gene name leucine rich repeat (in FLII) interacting protein 1
Synonyms name GC-binding factor 2
Locus 2q37, 3
Discovery year 1999-02-15
GenBank acession AJ223075
Entrez gene record 9208
Pubmed identfication 9705290 9525888 16199883
RefSeq identity NM_004735
Havana BLAST/BLAT OTTHUMG00000133339

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