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LSD1 / KDM1 Antibody

LSD1 / KDM1 Antibody size: 0.1mg 320

Supplier NJS POLY
Price 320
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLSD1 / KDM1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-2ug/ml, Western blot: 0
Notes LSD1 / KDM1 antibody titration may be required for optimal results, Provided assay concentrations are suggestions only
Added buffer pH 7, 1X Phosphate Buffered Saline (PBS), 4
Intented useThis LSD1 KDM1 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #23028
PurityPurified by protein A Affinity Chromatography
Description 2012), It also plays a role in tumor development where overexpression of LSD1 correlates with a poor prognosis, It is upregulated in cancers of the bladder, It negatively regulates pro-inflammatory cytokine expression by interacting with the genes promoter region, also called KDM1 (lysine (K)-specific demethylase 1A), and GI tract as well as neuroblastoma and cells of mesenchymal origin such as chondrosarcoma, breast, colon, is the first histone demethylase to be identified and regulates transcription via demethylation of lysines 4 and 9 of Histone H3, lung, osteosarcoma, rhabdomyosarcoma and Ewing's sarcoma (Bennani-Baiti et al, LSD1 (Lysine-specific demethylase 1)
ImmunogenA recombinant protein fragment from the N-terminal region of human LSD1 / KDM1 was used as the immunogen for this antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LSD1 / KDM1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene KDM1A
Gene targetLSD1 / KDM1
Short nameLSD1 / KDM1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLSD1 / KDM1 (Antibody to)
Alternative techniqueantibodies
Identity 29079
Long gene name lysine demethylase 1A
Synonyms gene AOF2 KDM1
Synonyms gene name amine oxidase (flavin containing) domain 2 lysine (K)-specific demethylase 1
Synonyms KIAA0601 BHC110 LSD1
Locus 1p36, 12
Discovery year 2004-02-26
GenBank acession AL031428
Entrez gene record 23028
Pubmed identfication 9628581 12493763
RefSeq identity NM_015013
Classification Lysine demethylases
Havana BLAST/BLAT OTTHUMG00000003220

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