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Lubricin/SZP Antibody

Lubricin/SZP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLubricin/SZP Primary Polyclonal Antibody
Also known asLubricin/SZP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLubricin/SZP
SpecificityThis is a highly specific antibody against Lubricin/SZP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lubricin/SZP
Gene ID number6401
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule, Defects in the gene encoding for lubricin can cause Jakobs syndrome, It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage, Lubricin inhibits synovial cell adhesion to the cartilage surface, Lubricin is highly expressed in cartilage, Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), also designated proteoglycan-4 or megakaryocyte stimulating factor, but also prevents the deposition of proteins from synovial fluid onto cartilage, is important for boundary lubrication within articulating joints, liver and synovial tissue, Lubricin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CACP, FLJ32635, HAPO, JCAP, Jacobs camptodactyly-arthropathy-pericarditis syndrome gene, MSF, PRG 4, PRG4, Proteoglycan4, SZP, Superficial zone proteoglycan, articular superficial zone protein, bG174L6, camptodactyly arthropathy coxa vara pericarditis syndrome gene, megakaryocyte stimulating factor, proteoglycan 4, 2, Superficial zone proteoglycan
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLubricin/SZP
Short nameLubricin/SZP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLubricin/SZP (Antibody to)
Alternative techniqueantibodies
Identity 9364
Gene PRG4
Long gene name proteoglycan 4
Synonyms gene CACP
Synonyms gene name (megakaryocyte stimulating factor, arthropathy, articular superficial zone protein, camptodactyly, coxa vara, pericarditis syndrome) , proteoglycan 4
Synonyms JCAP SZP MSF HAPO bG174L6, 2 FLJ32635
Synonyms name arthropathy, coxa vara, lubricin megakaryocyte stimulating factor articular superficial zone protein Jacobs camptodactyly-arthropathy-pericarditis syndrome camptodactyly, pericarditis syndrome bG174L6, 2 (MSF: megakaryocyte stimulating factor )
Locus 1q31, 1
Discovery year 2000-07-31
GenBank acession U70136
Entrez gene record 10216
Pubmed identfication 10545950 9920774
RefSeq identity NM_005807
Havana BLAST/BLAT OTTHUMG00000035574

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