Name : LYL1 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8693087012
| Long name | ALEXA FLUOR 647 Conjugated, LYL1 Polyclonal Antibody |
| Also known as | Anti-LYL1 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | LYL1 |
| Specificity | This is a highly specific antibody against LYL1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LYL1 |
| Gene ID Number | 4066 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Endogenous Lyl-1 exists in complex with E2&, Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein, Lyl-1 and E2&, Lyl-1 is involved in a chromosomal aberration which causes a form of T cell acute lymphoblastic leukemia (T-ALL), Lyl1 is highly expressed in most AML cell lines, TAL1, TAL1 and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia, TAL2 includes a helix-loop-helix protein dimerization and DNA-binding domain that is homologous to TAL1 and Lyl-1 proto-oncogenes, TAL2 is a protein involved in T cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and T cell receptor â, The expression of Lyl1 is at higher levels in the majority of cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow, also designated SCL, chain genes, is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis, protein can form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells, proteins, &circ, &euro, &euro, «, &ldquo, &ldquo, Lyl-1, The Lyl1 gene encodes a basic helixâ, aring, aring, helix transcription factor involved in T-cell acute lymphoblastic leukemia, loopâ |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | bHLHa18 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the LYL1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | LYL1 |
| Short name | LYL1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, lymphoblastic leukemia derived sequence 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0030183 and B cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0060216 and definitive hemopoiesis and biological process, LYL1 and IDBG-31743 and ENSG00000104903 and 4066, LYL1 and IDBG-642860 and ENSBTAG00000019329 and 615458, Lyl1 and IDBG-174653 and ENSMUSG00000034041 and 17095, bHLHa18, nuclei, protein dimerization activity, this GO :0001955 and blood vessel maturation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0005515: protein binding and also this GO :0046983: protein dimerization activity, this GO :0005515: protein binding, this GO :0046983: protein dimerization activity, lymphoblastic leukemia derived sequence 1 |
| Identity | 6734 |
| Gene | LYL1 |
| Long gene name | LYL1, basic helix-loop-helix family member |
| Synonyms gene name | lymphoblastic leukemia derived sequence 1 lymphoblastic leukemia associated hematopoiesis regulator 1 |
| Locus | 19p13, 13 |
| Discovery year | 1990-03-21 |
| Entrez gene record | 4066 |
| Pubmed identfication | 2752424 |
| RefSeq identity | NM_005583 |
| Classification | Basic helix-loop-helix proteins |
| Havana BLAST/BLAT | OTTHUMG00000180736 |