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LYRIC Antibody (Metadherin)

LYRIC Antibody (Metadherin) size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLYRIC (Metadherin)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the LYRIC antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis LYRIC antibodyis to be used only for research purposes and not for diagnostics
Gene ID #92140
PurityAntigen affinity
Description It is highly expressed in these cancers and helps in progression and development of these cancers, It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells, It is involved in <, LYRIC acts as an oncogene in melanoma, LYRIC induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis, Late SV40 factor enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (<, also known as LYRIC or astrocyte elevated gene-1 protein (AEG-1), and plays a very important role in RISC and miRNA functions, breast cancer and hepatocellular carcinoma, interacts with SND1 and is involved in RNA-induced silencing complex (RISC), is a protein that in humans is encoded by the MTDH gene, malignant glioma, mediated angiogenesis, ), /a>, /a>, /search_result, /search_result, HIF-1 alpha<, MMP9<, MTDH (Metadherin), a href=, a href=, php?search_txt=hif-1 alpha>, php?search_txt=mmp9>
ImmunogenHuman partial recombinant protein (AA 101-270) was used as the immunogen for this LYRIC antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LYRIC antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetLYRIC (Metadherin)
Short nameLYRIC Antibody (Metadherin)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLYRIC (Antibody to) (Metadherin)
Alternative techniqueantibodies
Identity 29608
Gene MTDH
Long gene name metadherin
Synonyms LYRIC 3D3 AEG-1
Synonyms name astrocyte elevated gene 1
Locus 8q22, 1
Discovery year 2005-07-18
GenBank acession AF411226
Entrez gene record 92140
Pubmed identfication 15093543
Havana BLAST/BLAT OTTHUMG00000164692

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