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MAC-1 Antibody

MAC-1 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMAC-1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MAC-1 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #3684
PurityAntigen affinity
Description Additionally, It is implicated in various adhesive interactions of monocytes, It is mapped to 16p11, MAC-1 has a role in vascular repair after mechanical arterial injury, and it is also a receptor for fibrinogen, factor X and ICAM1, it likely recognizes the R-G-D peptide in C3b, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles, 2, Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene
ImmunogenHuman partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MAC-1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMAC-1
Short nameMAC-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMAC-1 (Antibody to)
Alternative techniqueantibodies
Identity 6149
Gene ITGAM
Long gene name integrin subunit alpha M
Synonyms gene CR3A CD11B
Synonyms gene name alpha, alpha M (complement component 3 receptor 3 subunit) , alpha M (complement component receptor 3, also known as CD11b (p170), integrin, macrophage antigen alpha polypeptide) integrin
Synonyms MAC-1 CD11b
Synonyms name complement component 3 receptor 3 subunit
Locus 16p11, 2
Discovery year 1988-08-05
GenBank acession J03925
Entrez gene record 3684
RefSeq identity NM_000632
Classification Complement system Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000176612

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