Name : MAML1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7430308060
| Long name | MAML1 Primary Polyclonal Antibody |
| Also known as | MAML1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MAML1 |
| Specificity | This is a highly specific antibody against MAML1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAML1 |
| Gene ID number | 9794 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In Drosophila, Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5), The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2), The gene which encodes Mam1 maps to human chromosome 5 (4), The human homolog, and amplifies Notch-induced transcription of Hes1 (2), and humans (1), forms a DNA-binding complex with ICN and RBP-Jk, frogs, localizes to nuclear bodies (2-4), loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2), mastermind-like 1 (Mam1), Notch receptors are involved in cell-fate determination in organisms as diverse as flies |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MAML 1, MAML 1, MAML1_HUMAN, Mam1, Maml1, Mastermind like 1, Mastermind-like protein 1, mKIAA0200, Mam-1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MAML1 |
| Short name | MAML1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MAML1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13632 |
| Gene | MAML1 |
| Long gene name | mastermind like transcriptional coactivator 1 |
| Synonyms gene name | mastermind (drosophila)-like 1 mastermind-like 1 (Drosophila) |
| Synonyms | KIAA0200 Mam-1 |
| Synonyms name | mastermind homolog |
| Locus | 5q35, 3 |
| Discovery year | 2001-07-19 |
| GenBank acession | D83785 |
| Entrez gene record | 9794 |
| Pubmed identfication | 11101851 11390662 |
| RefSeq identity | NM_014757 |
| Havana BLAST/BLAT | OTTHUMG00000163237 |