Name : MAML2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4162320158
| Long name | Biotin Conjugated, MAML2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MAML2 |
| Specificity | This is a highly specific antibody against MAML2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human MAML2 |
| Gene ID number | 84441 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | In Drosophila, Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5), The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2), The gene which encodes Mam1 maps to human chromosome 5 (4), The human homolog, and amplifies Notch-induced transcription of Hes1 (2), and humans (1), forms a DNA-binding complex with ICN and RBP-Jk, frogs, localizes to nuclear bodies (2-4), loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2), mastermind-like 1 (Mam1), Notch receptors are involved in cell-fate determination in organisms as diverse as flies |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | KIAA1819 MAM3 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MAML2 Conjugated |
| Short name | Conjugated, MAML2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, MAML2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16259 |
| Gene | MAML2 |
| Long gene name | mastermind like transcriptional coactivator 2 |
| Synonyms gene name | mastermind (Drosophila)-like 2 mastermind-like 2 (Drosophila) |
| Locus | 11q21 |
| Discovery year | 2002-11-04 |
| GenBank acession | AB058722 |
| Entrez gene record | 84441 |
| Pubmed identfication | 12370315 12386158 |
| Havana BLAST/BLAT | OTTHUMG00000167677 |