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MAML2 Antibody, FITC Conjugated

MAML2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, MAML2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMAML2
SpecificityThis is a highly specific antibody against MAML2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MAML2
Gene ID number84441
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In Drosophila, Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5), The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2), The gene which encodes Mam1 maps to human chromosome 5 (4), The human homolog, and amplifies Notch-induced transcription of Hes1 (2), and humans (1), forms a DNA-binding complex with ICN and RBP-Jk, frogs, localizes to nuclear bodies (2-4), loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2), mastermind-like 1 (Mam1), Notch receptors are involved in cell-fate determination in organisms as diverse as flies
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms KIAA1819 MAM3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMAML2 Conjugated
Short name FITC Conjugated, MAML2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MAML2 (Antibody to)
Alternative techniqueantibodies
Identity 16259
Gene MAML2
Long gene name mastermind like transcriptional coactivator 2
Synonyms gene name mastermind (Drosophila)-like 2 mastermind-like 2 (Drosophila)
Locus 11q21
Discovery year 2002-11-04
GenBank acession AB058722
Entrez gene record 84441
Pubmed identfication 12370315 12386158
Havana BLAST/BLAT OTTHUMG00000167677

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