| Alternative name1 | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, Anti-MAP Kinase p44/42 |
| Alternative name2 | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, MAP Kinase p44/42 |
| Alternative name3 | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, MAP Kinase p44/42 |
| Alternative name4 | MAP Kinase p44/42 |
| Alternative name5 | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, Anti -MAP Kinase p44/42 |
| Other names | N/A, MAP kinase |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Sheep |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | Species crossreactivity, Specific for phosphorylated Erk1 and Erk2 (42-44kD) |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 0, 0, before the addition of glycerl to 30%, pH 7, 05% sodium azide, 15M sodium chloride, 2M Tris-glycine, 4, Supplied as a liquid in 0 |
| Concentration | N/A |
| Storage and shipping | For maximum recovery of product, Further dilutions can be made in assay buffer, Long-term storage should be done after aliquoting the item and freezing the aliqotes at -20 degrees Celsius, Under these conditions the aliquots will be stable for at least one year if kept at -20 °, centrifuge the original vial after thawing and prior to removing the cap, C, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunoprecipitation (IP), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, MAP Kinase p44/42 |
| Short name | ERK, ERK-2, ERT1, Extracellular Signal-regulated Kinase 2, MAP Kinase 1, MAP Kinase 2, MAP Kinase Isoform p42, MAPK 1, MAPK 2, Mitogen-activated Protein Kinase 1, Mitogen-activated Protein Kinase 2, p42-MAPK, phosphorylated (MAPK3/MAPK1, MAP Kinase p44/42 |
| Alternative name | ERK, ERK-2, ERT1, Extracellular Signal-regulated phosphorylation catalyst 2, MAPK 1, MAPK 2, Mitogen-activated Protein phosphorylation catalyst 1, Mitogen-activated Protein phosphorylation catalyst 2, mitogen-stimulated protein kinase phosphorylation catalyst 1, mitogen-stimulated protein kinase phosphorylation catalyst 2, mitogen-stimulated protein kinase phosphorylation catalyst Isoform p42, p42-MAPK, phosphorylated (mitogen-activated protein kinase 3/mitogen-activated protein kinase 1, mitogen-stimulated protein kinase phosphorylation catalyst p44/42 |
| Alternative to gene target | DNA-templated and biological process this GO :0006360 and transcription from RNA polymerase I promoter and biological process this GO :0006361 and transcription initiation from RNA polymerase I promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0007049 and cell cycle and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016032 and viral process and biological process this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006935 and chemotaxis and biological process this GO :0006950 and response to stress and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007049 and cell cycle and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008353 and RNA polymerase II carboxy-terminal domain kinase activity and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010800 and positive regulation of peptidyl-threonine phosphorylation and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016032 and viral process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060716 and labyrinthine layer blood vessel development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070849 and response to epidermal growth factor and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0072584 and caveolin-mediated endocytosis and biological process this GO :0072686 and mitotic spindle and cellular component this GO :0090170 and regulation of this GO lgi inheritance and biological process this GO :0097011 and cellular response to granulocyte macrophage colony-stimulating factor stimulus and biological process this GO :2000641 and regulation of early endosome to late endosome transport and biological process, ERK and ERK-2 and ERK2 and ERT1 and MAPK2 and p38 and p40 and p41 and p41mapk and p42-MAPK and P42MAPK and PRKM1 and PRKM2, ERK-1 and ERK1 and ERT2 and HS44KDAP and HUMKER1A and p44-ERK1 and p44-MAPK and P44ERK1 and P44MAPK and PRKM3, MAPK1 and IDBG-2147 and ENSG00000100030 and 5594, MAPK1 and IDBG-637539 and ENSBTAG00000010312 and 327672, MAPK3 and IDBG-25745 and ENSG00000102882 and 5595, MAPK3 and IDBG-639178 and ENSBTAG00000016156 and 531391, Mapk1 and IDBG-137672 and ENSMUSG00000063358 and 26413, Mapk3 and IDBG-209781 and ENSMUSG00000063065 and 26417, mitogen-activated protein kinase 3, nuclei, nuclei, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0000189 and MAPK import into nucleus and biological process this GO :0001784 and phosphotyrosine binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004707 and MAP kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005815 and microtubule organizing center and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005901 and caveola and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006351 and transcription, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0001784 and phosphotyrosine binding and molecular function this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004707 and MAP kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005901 and caveola and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006351 and transcription, this GO :0001784: phosphotyrosine binding, this GO :0001784: phosphotyrosine binding, this GO :0001784: phosphotyrosine binding and also this GO :0003677: DNA binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004707: MAP kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008134: transcription factor binding and also this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, this GO :0001784: phosphotyrosine binding and also this GO :0004672: protein kinase activity and also this GO :0004707: MAP kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0003677: DNA binding, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004707: MAP kinase activity, this GO :0004707: MAP kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005524: ATP binding, this GO :0008134: transcription factor binding, this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity, this GO :0016301: kinase activity, this GO :0016772: transferase activity, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0019902: phosphatase binding, this GO :0019902: phosphatase binding, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0019902: phosphatase binding and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding, transferring phosphorus-containing groups and also this GO :0019902: phosphatase binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019858 and cytosine metabolic process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019902 and phosphatase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0031143 and pseudopodium and cellular component this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0031647 and regulation of protein stability and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032839 and dendrite cytoplasm and cellular component this GO :0032872 and regulation of stress-activated MAPK cascade and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0038127 and ERBB signaling pathway and biological process this GO :0043204 and perikaryon and cellular component this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043627 and response to estrogen and biological process this GO :0045087 and innate immune response and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045893 and positive regulation of transcription, transferring phosphorus-containing groups and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019902 and phosphatase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0031143 and pseudopodium and cellular component this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032872 and regulation of stress-activated MAPK cascade and biological process this GO :0033129 and positive regulation of histone phosphorylation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035066 and positive regulation of histone acetylation and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051216 and cartilage development and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070498 and interleukin-1-mediated signaling pathway and biological process this GO :0070849 and response to epidermal growth factor and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0072584 and caveolin-mediated endocytosis and biological process this GO :0090170 and regulation of this GO lgi inheritance and biological process this GO :2000641 and regulation of early endosome to late endosome transport and biological process this GO :2000657 and negative regulation of apolipoprotein binding and biological process, mitogen-activated protein kinase 1 |
| Identity | 6877 |
| Gene | MAPK3 |
| Long gene name | mitogen-activated protein kinase 3 |
| Synonyms gene | PRKM3 |
| Synonyms | ERK1 p44mapk p44erk1 |
| Locus | 16p11, 2 |
| Discovery year | 1993-11-05 |
| GenBank acession | M84490 |
| Entrez gene record | 5595 |
| Pubmed identfication | 9628824 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000132149 |
Technique
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