Name : MAP1A/MAP1B LC3 A/B Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5241553975
| Long name | ALEXA FLUOR 350 Conjugated, MAP1A/MAP1B LC3 A/B Antibody |
| Also known as | Anti-MAP1A/MAP1B LC3 A/B PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MAP1A/MAP1B LC3 A/B |
| Specificity | This is a highly specific antibody against MAP1A/MAP1B LC3 A/B |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 20-70/121 |
| Subcellular location | Cell membrane, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B |
| Gene ID Number | 81631, 84557 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A disruption to the autophagic process is now associated with the progression of several cancers, LC3, LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), This process of internal cellular turn-over is called autophagy (self-eating), a ubiquitin-like modifier protein, and is facilitated by a pathway of around 16 interacting proteins in the human, called autophagosomes, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, neurodegenerative disorders and cardiac pathologies, respectively, termed LC3-I and LC3-II, where LC3 is widely employed as a marker for autophagy, which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | MAP1A/MAP1B LC3 A/B |
| Short name | MAP1A/MAP1B LC3 A/B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, MAP1A/MAP1B LC3 A/B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6835 |
| Gene | MAP1A |
| Long gene name | microtubule associated protein 1A |
| Synonyms gene | MAP1L |
| Locus | 15q15, 3 |
| Discovery year | 1992-07-09 |
| GenBank acession | U38292 |
| Entrez gene record | 4130 |
| Pubmed identfication | 7806212 7629894 |
| RefSeq identity | NM_002373 |
| Havana BLAST/BLAT | OTTHUMG00000059756 |