Name : MAP3K11 (230CT5.3.1) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN4930093238
| Long name | 1) Monoclonal Antibody, 3, MAP3K11 (230CT5 |
| Also known as | 1) Monoclonal Antibody, 3, MAP3K11 (230CT5 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MAP3K11 |
| Specificity | This is a highly specific antibody against MAP3K11 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 230CT5, 3 |
| Source | This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein |
| Gene ID number | 4296 |
| Swiss Prot | Q16584 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~500) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Influences microtubule organization during the cell cycle, MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7, Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), but does not phosphorylate BRAF directly, Activates the JUN N-terminal pathway |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MAP3K11, MEKK11, MLK-3, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, PTK1, SPRK, Src-homology 3 domain-containing proline-rich kinase, MLK3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1) Monoclonal, 3, MAP3K11 (230CT5 |
| Short name | 1) Monoclonal Antibody, 3, MAP3K11 (230CT5 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1) monoclonal (Antibody to), 3, mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst 11 (230CT5 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, MAP3K11 and IDBG-57450 and ENSG00000173327 and 4296, MEKK11 and MLK-3 and MLK3 and PTK1 and SPRK, Map3k11 and IDBG-132706 and ENSMUSG00000004054 and 26403, Plasma membranes, this GO :0000080 and mitotic G1 phase and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004706 and JUN kinase kinase kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005874 and microtubule and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007017 and microtubule-based process and biological process this GO :0007254 and JNK cascade and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008219 and cell death and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004706: JUN kinase kinase kinase activity and also this GO :0004709: MAP kinase kinase kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004706: JUN kinase kinase kinase activity, this GO :0004709: MAP kinase kinase kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0031434: mitogen-activated protein kinase kinase binding, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0048365: Rac GTPase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031434: mitogen-activated protein kinase kinase binding and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0048365: Rac GTPase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0031434 and mitogen-activated protein kinase kinase binding and molecular function this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048365 and Rac GTPase binding and molecular function, 27525 and IDBG-644205 and ENSBTAG00000004114 and 514210, mitogen-activated protein kinase kinase kinase 11 |
| Identity | 6850 |
| Gene | MAP3K11 |
| Long gene name | mitogen-activated protein kinase kinase kinase 11 |
| Synonyms gene | MLK3 PTK1 |
| Synonyms | SPRK MEKK11 |
| Locus | 11q13, 1 |
| Discovery year | 1992-10-02 |
| Entrez gene record | 4296 |
| Pubmed identfication | 9267807 8183572 |
| Classification | Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000166529 |