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MAP3K8 Antibody, ALEXA FLUOR 350

MAP3K8 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, MAP3K8 Polyclonal Antibody
Also known asAnti-MAP3K8 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMAP3K8
SpecificityThis is a highly specific antibody against MAP3K8
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-190/467
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP3K8
Gene ID Number1326
Swiss ProtP41279
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen In adipocytes, In vitro, Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production, Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells, Isoform 1 shows some transforming activity, May also play a role in the transduction of TNF signals that activate JNK and NF-kappa-B in some cell types, Plays a role in the cell cycle, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, Transduces CD40 and TNFRSF1A signals that activate ERK in B-cells and macrophages, activates MAPK/ERK pathway in an IKBKB-dependent manner in response to IL1B and TNF, activates MAPK/ERK pathway in response to IL1 in an IRAK1-independent manner, although it is much weaker than that of the activated oncogenic variant, and thus may play a role in the regulation of immunoglobulin production, but not insulin, leading to induction of lipolysis, leading to up-regulation of IL8 and CCL4, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses, Required for lipopolysaccharide (LPS)-induced
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms Tpl-2 EST c-COT MEKK8
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetMAP3K8
Short nameMAP3K8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, MAP3K8 (Antibody to)
Alternative techniqueantibodies
Identity 6860
Gene MAP3K8
Long gene name mitogen-activated protein kinase kinase kinase 8
Synonyms gene COT ESTF
Locus 10p11, 23
Discovery year 1992-09-14
GenBank acession D14497
Entrez gene record 1326
Pubmed identfication 2072910 8479752
RefSeq identity NM_005204
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000017889

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