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MAPKAP Kinase 2 Antibody, ALEXA FLUOR 555

MAPKAP Kinase 2 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, MAPKAP Kinase 2 Polyclonal Antibody
Also known asAnti-MAPKAP Kinase 2 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMAPKAP Kinase 2
SpecificityThis is a highly specific antibody against MAPKAP Kinase 2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range337-363/400
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAPKAP Kinase 2
Gene ID Number9261
Swiss ProtP49137
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Bovine, Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also involved in late G2/M checkpoint following DNA damage through a process of post-transcriptional mRNA stabilization: following DNA damage, CDC25B, CDC25C, DNA damage response and transcriptional regulation, ELAVL1, Following stress, HNRNPA, HNRNPA, HSF1, HSP27/HSPB1, Hyd-X-R-X(2)-S, Involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating AU-rich elements (AREs)-binding proteins ELAVL1, Involved in toll-like receptor signaling pathway (TLR) in dendritic cells: required for acute TLR-induced macropinocytosis by phosphorylating and activating RPS6KA3, KRT18, KRT2, LIMK1, LSP1, Mediates phosphorylation of HSP27/HSPB1 in response to stress, PABPC1, PABPC1 and TTP/ZFP36, PARN, PDE4A, Phosphorylates ALOX5, Phosphorylates serine in the peptide sequence, Phosphorylation of TTP/ZFP36, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36, a major post-transcriptional regulator of TNF, cell cycle control, cell migration, chromatin remodeling, endocytosis, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair their chaperone activities and ability to protect against oxidative stress effectively, leading to phosphorylation of substrates, leading to regulate the stability and translation of TNF and IL6 mRNAs, leading to stabilize GADD45A mRNA, promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity leading to inhibition of dependent degradation of ARE-containing transcript, relocalizes from nucleus to cytoplasm and phosphorylates HNRNPA and PARN, reorganization of the cytoskeleton, where Hyd is a large hydrophobic residue, Stress-activated serine/threonine-protein kinase involved in cytokines production
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAP-K2, MAPKAPK-2, MAPKAPK2, MK-2, MK2
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetMAPKAP Kinase 2
Short nameMAPKAP Kinase 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, MAPKAP phosphorylation catalyst 2 (Antibody to)
Alternative techniqueantibodies

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