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MAPKAP kinase 5 (13H5) Monoclonal Antibody

MAPKAP kinase 5 (13H5) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMAPKAP kinase 5 (13H5) Monoclonal Antibody
Also known asMAPKAP kinase 5 (13H5) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMAPKAP kinase 5
SpecificityThis is a highly specific antibody against MAPKAP kinase 5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number13H5
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli (His-PRAK)
Gene ID number8550
Swiss ProtQ8IW41
Tested ApplicationsWB
Recommended dilutions5 ug/mL), WB (0
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation, Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB, Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53, ERK3/MAPK6, ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, ERK4/MAPK4, HSP27/HSPB1, Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, Phosphorylates FOXO3, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), enabling expression of miR-34b and miR-34c, inducing F-actin rearrangement, p53/TP53 and RHEB, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4), Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPKAP kinase 5, MAPKAP-K5, MAPKAPK-5, MAPKAPK5, MK-5, PRAK, p38-regulated/activated protein kinase, MK5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetMAPKAP kinase 5 (13H5) Monoclonal
Short nameMAPKAP kinase 5 (13H5) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameMAPKAP phosphorylation catalyst 5 (13H5) monoclonal (Antibody to)
Alternative techniqueantibodies

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