Filters

MAPKAPK5(Thr182) Antibody, Cy7 Conjugated

MAPKAPK5(Thr182) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, MAPKAPK5(Thr182) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMAPKAPK5 Thr182
Specificity This phosphorylation site is homologous to that of Thr182 in Mouse, This is a highly specific antibody against MAPKAPK5 Thr182
ModificationPhosphorylation
Modification siteThr182
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range160-210/473
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MAPKAPK5 around the phosphorylation site of Thr182
Gene ID number8550
Swiss ProtQ8IW41
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation, Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB, Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53, ERK3/MAPK6, ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, ERK4/MAPK4, HSP27/HSPB1, Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, Phosphorylates FOXO3, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), enabling expression of miR-34b and miR-34c, inducing F-actin rearrangement, p53/TP53 and RHEB, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4), Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms PRAK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetMAPKAPK5(Thr182) Conjugated
Short name Conjugated, MAPKAPK5(Thr182) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, MAPKAPK5(Thr182) (Antibody to)
Alternative techniqueantibodies
Identity 6889
Gene MAPKAPK5
Long gene name mitogen-activated protein kinase-activated protein kinase 5
Locus 12q24, 12-q24, 13
Discovery year 1999-03-26
GenBank acession AF032437
Entrez gene record 8550
Pubmed identfication 9628874
RefSeq identity NM_139078
Classification Mitogen-activated protein kinase-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000169605

Similar products

Subscribe to our Newsletter