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MARCH2 Antibody

MARCH2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMARCH2 Primary Polyclonal Antibody
Also known asMARCH2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigen37316
SpecificityThis is a highly specific antibody against 37316
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH2
Gene ID number51257
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Expressed in a variety of tissues, MARCH2 (membrane-associated ring finger (C3HC4) 2), MARCH2 functions as an E3 ubiquitin-protein ligase that is thought to mediate the ubiquitination and subsequent degradation of CD71 and B7-2 and may be involved in endosomal protein trafficking, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF172 or HSPC240, is a 246 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E3 ubiquitin-protein ligase MARCH2, EC 6, MARCH II, MARCH-II, MARH2_HUMAN antibody Membrane associated RING CH protein II, Membrane associated RING finger protein 2, Membrane associated ring finger C3HC4 2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, RING finger protein 172, RNF172, march2, - antibody HSPC240, 2, 3, E3 ubiquitin protein ligase MARCH2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH2
Short nameMARCH2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name E3 ubiquitin protein ligase (Antibody to), membrane-associated ring finger (C3HC4) 2
Alternative techniqueantibodies
Alternative to gene target E3 ubiquitin protein ligase, MARCH2 and IDBG-24762 and ENSG00000099785 and 51257, MARCH2 and IDBG-643827 and ENSBTAG00000021036 and 508949, March2 and IDBG-251885 and ENSMUSG00000079557 and 224703, Plasma membranes, metal ion binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0046872: metal ion binding, membrane-associated ring finger (C3HC4) 2
Identity 28038
Gene MARCH2
Long gene name membrane associated ring-CH-type finger 2
Synonyms gene name E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 2 membrane-associated ring finger (C3HC4) 2
Synonyms HSPC240 MARCH-II RNF172
Locus 19p13, 2
Discovery year 2005-01-26
GenBank acession AF151074
Entrez gene record 51257
Pubmed identfication 11042152 14722266
RefSeq identity NM_016496
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000182282

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