Name : MARCH3 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7163972385
| Long name | ALEXA FLUOR 555 Conjugated, MARCH3 Polyclonal Antibody |
| Also known as | Anti-37681 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | 37681 |
| Specificity | This is a highly specific antibody against 37681 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH3 |
| Gene ID Number | 115123 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Involved in the pathway of protein modification, MARCH3 (membrane-associated ring finger (C3HC4) 3), MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | MGC48332 MARCH-III RNF173 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | MARCH3 |
| Short name | MARCH3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, E3 ubiquitin protein ligase (Antibody to), membrane-associated ring finger (C3HC4) 3 |
| Alternative technique | antibodies |
| Alternative to gene target | E3 ubiquitin protein ligase, MARCH3 and IDBG-39523 and ENSG00000173926 and 115123, MARCH3 and IDBG-644898 and ENSBTAG00000006797 and 520348, March3 and IDBG-148017 and ENSMUSG00000032656 and 320253, Plasma membranes, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0046872: metal ion binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0046872: metal ion binding, membrane-associated ring finger (C3HC4) 3 |
| Identity | 28728 |
| Gene | MARCH3 |
| Long gene name | membrane associated ring-CH-type finger 3 |
| Synonyms gene name | E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 3 membrane-associated ring finger (C3HC4) 3 |
| Locus | 5q23, 2 |
| Discovery year | 2005-01-26 |
| GenBank acession | AF055007 |
| Entrez gene record | 115123 |
| Pubmed identfication | 14722266 8619474 |
| RefSeq identity | NM_178450 |
| Classification | Membrane associated ring-CH-type fingers Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000128968 |