Filters

MARCH8 Antibody, Biotin Conjugated

MARCH8 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, MARCH8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigen39508
SpecificityThis is a highly specific antibody against 39508
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MARCH8
Gene ID number220972
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Expressed in a variety of tissues, MARCH8 (membrane-associated ring finger (C3HC4) 8), MARCH8 functions as an E3 ubiquitin ligase that is thought to regulate immune responses by promoting the ubiquitination and subsequent degradation of target proteins, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, also known as MIR or RNF178 (RING finger protein 178), including immature dendritic cells, is a 291 amino acid multi-pass membrane protein that localizes to vesicle membranes and contains one RING-CH-type zinc finger, such as B7-2 and CD71, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms c-MIR CMIR MARCH-VIII RNF178
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH8 Conjugated
Short name Conjugated, MARCH8 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MARCH8 (Antibody to)
Alternative techniqueantibodies
Identity 23356
Gene MARCH8
Long gene name membrane associated ring-CH-type finger 8
Synonyms gene MIR
Synonyms gene name E3 ubiquitin protein ligase , c-mir, cellular modulator of immune recognition membrane-associated ring finger (C3HC4) 8 membrane-associated ring finger (C3HC4) 8
Locus 10q11, 21-q11, 22
Discovery year 2003-11-12
GenBank acession AL833316
Entrez gene record 220972
Pubmed identfication 12582153 14722266
RefSeq identity NM_145021
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000019345

Subscribe to our Newsletter