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MARCH8 Antibody, FITC Conjugated

MARCH8 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, MARCH8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigen39508
SpecificityThis is a highly specific antibody against 39508
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MARCH8
Gene ID number220972
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Expressed in a variety of tissues, MARCH8 (membrane-associated ring finger (C3HC4) 8), MARCH8 functions as an E3 ubiquitin ligase that is thought to regulate immune responses by promoting the ubiquitination and subsequent degradation of target proteins, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, also known as MIR or RNF178 (RING finger protein 178), including immature dendritic cells, is a 291 amino acid multi-pass membrane protein that localizes to vesicle membranes and contains one RING-CH-type zinc finger, such as B7-2 and CD71, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms c-MIR CMIR MARCH-VIII RNF178
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH8 Conjugated
Short name FITC Conjugated, MARCH8 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MARCH8 (Antibody to)
Alternative techniqueantibodies
Identity 23356
Gene MARCH8
Long gene name membrane associated ring-CH-type finger 8
Synonyms gene MIR
Synonyms gene name E3 ubiquitin protein ligase , c-mir, cellular modulator of immune recognition membrane-associated ring finger (C3HC4) 8 membrane-associated ring finger (C3HC4) 8
Locus 10q11, 21-q11, 22
Discovery year 2003-11-12
GenBank acession AL833316
Entrez gene record 220972
Pubmed identfication 12582153 14722266
RefSeq identity NM_145021
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000019345

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