Name : MASTL (235CT7.8.2.3) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN9359237650
| Long name | 2, 3) Monoclonal Antibody, 8, MASTL (235CT7 |
| Also known as | 2, 3) Monoclonal Antibody, 8, MASTL (235CT7 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MASTL |
| Specificity | This is a highly specific antibody against MASTL |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 2, 235CT7, 3, 8 |
| Source | This MASTL monoclonal antibody is generated from mouse immunized with MASTL recombinant protein |
| Gene ID number | 84930 |
| Swiss Prot | Q96GX5 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:1000~16000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A, Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', Following DNA damage, Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high, May be involved in megakaryocyte differentiation, Phosphorylates histone protein in vitro, however such activity is unsure in vivo, it is also involved in checkpoint recovery by being inhibited, respectively, Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GREATWALL, GWL, MAST-L, MASTL, Microtubule-associated serine/threonine-protein kinase-like, Serine/threonine-protein kinase greatwall, THC2, hGWL, GW |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 2, 3) Monoclonal, 8, MASTL (235CT7 |
| Short name | 2, 3) Monoclonal Antibody, 8, MASTL (235CT7 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 2, 3) monoclonal (Antibody to), 8, MASTL (235CT7 |
| Alternative technique | antibodies |
| Identity | 19042 |
| Gene | MASTL |
| Long gene name | microtubule associated serine/threonine kinase like |
| Synonyms gene name | microtubule associated serine/threonine kinase-like |
| Synonyms | FLJ14813 THC2 Gwl |
| Synonyms name | greatwall kinase homolog |
| Locus | 10p12, 1 |
| Discovery year | 2004-02-10 |
| GenBank acession | BC009107 |
| Entrez gene record | 84930 |
| RefSeq identity | NM_032844 |
| Havana BLAST/BLAT | OTTHUMG00000017855 |