| Long name | MAVS Primary Polyclonal Antibody |
| Also known as | MAVS PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MAVS |
| Specificity | This is a highly specific antibody against MAVS |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAVS |
| Gene ID number | 5788 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity, MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CARD, Card, DKFZp547C224, DKFZp666M015, FLJ27482, FLJ31698, FLJ35386, FLJ38051, FLJ41962, IPS-1, IPS1, Interferon beta promoter stimulator protein 1, Interferon-beta promoter stimulator protein 1, Ips 1, Ips1, KIAA1271, MAVS_HUMAN, MGC3260, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, Mitochondrial antiviral signaling protein, Putative NF kappa B activating protein 031N, VISA, Virus induced signaling adapter, CARD adapter inducing interferon beta |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MAVS |
| Short name | MAVS Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | mitochondrial antiviral signaling protein (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CARD domain binding, MAVS and IDBG-49080 and ENSG00000088888 and 57506, Mavs and IDBG-207066 and ENSMUSG00000037523 and 228607, Plasma membranes, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding and also this GO :0050700: CARD domain binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, this GO :0050700: CARD domain binding, translocation and biological process this GO :0039529 and RIG-I signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0060340 and positive regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071651 and positive regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0071660 and positive regulation of IP-10 production and biological process this GO :1900063 and regulation of peroxisome organization and biological process, 45349 and IDBG-640031 and ENSBTAG00000013545 and 618508, mitochondrial antiviral signaling protein |
| Identity | 29233 |
| Gene | MAVS |
| Long gene name | mitochondrial antiviral signaling protein |
| Synonyms | VISA KIAA1271 IPS-1 Cardif |
| Synonyms name | virus-induced signaling adaptor IFN-B promoter stimulator 1 CARD adaptor inducing IFN-beta |
| Locus | 20p13 |
| Discovery year | 2009-04-01 |
| GenBank acession | DQ174270 |
| Entrez gene record | 57506 |
| Pubmed identfication | 16125763 16153868 |
| RefSeq identity | NM_020746 |
| Classification | Caspase recruitment domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031765 |
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