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MBD2 Antibody

MBD2 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMBD2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MBD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MBD2 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #8932
PurityAntigen affinity
Description DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development, Each of these proteins, Human proteins MECP2, It is also reported that this protein functions as a demethylase to activate transcription, It is mapped to 18q21, MBD1, MBD2, MBD3, The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD), as DNA methylation causes gene silencing, is capable of binding specifically to methylated DNA, with the exception of MBD3, 2, Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene
ImmunogenHuman partial recombinant protein (AA 159-411) was used as the immunogen for this MBD2 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MBD2 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMBD2
Short nameMBD2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMBD2 (Antibody to)
Alternative techniqueantibodies
Identity 6917
Gene MBD2
Long gene name methyl-CpG binding domain protein 2
Locus 18q21, 2
Discovery year 1999-01-11
GenBank acession AF072242
Entrez gene record 8932
Pubmed identfication 9774669 10441743
RefSeq identity NM_003927
Classification NuRD complex Methyl-CpG binding domain containing
Havana BLAST/BLAT OTTHUMG00000132705

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