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MBP Antibody, Biotin Conjugated

MBP Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, MBP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMBP
SpecificityThis is a highly specific antibody against MBP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range45-87/167
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from Guinea Pig MBP
Tested applications IHC-F, IHC-P, WB
Recommended dilutions IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis, They have a role in both its formation and stabilization, and may also be involved in signaling pathways in T cells and neural cells, each of them having maybe a specialized function, maybe as components of transcriptional complexes, Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMBP Conjugated
Short name Conjugated, MBP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MBP (Antibody to)
Alternative techniqueantibodies
Identity 6925
Gene MBP
Long gene name myelin basic protein
Locus 18q23
Discovery year 1986-01-01
Entrez gene record 4155
Pubmed identfication 2425357
RefSeq identity NM_001025081
Havana BLAST/BLAT OTTHUMG00000132874

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