Name : MBP(Thr232) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5905608867
| Long name | MBP(Thr232) Primary Polyclonal Antibody |
| Also known as | MBP(Thr232) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MBP Thr232 |
| Specificity | This antibody recognizes Thr229 in mice and Thr122 in rat, This is a highly specific antibody against MBP Thr232 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr232 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 225-235/304 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Thr232 |
| Gene ID number | 4155 |
| Swiss Prot | P02686 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, Induces T-cell proliferation, The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis, They have a role in both its formation and stabilization, and may also be involved in signaling pathways in T-cells and neural cells, maybe as components of transcriptional complexes, with each of them potentially having a specialized function, The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein, Myelin basic protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MBP(Thr232) |
| Short name | MBP(Thr232) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MBP(Thr232) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6925 |
| Gene | MBP |
| Long gene name | myelin basic protein |
| Locus | 18q23 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 4155 |
| Pubmed identfication | 2425357 |
| RefSeq identity | NM_001025081 |
| Havana BLAST/BLAT | OTTHUMG00000132874 |