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MBP(Thr232) Antibody, Biotin Conjugated

MBP(Thr232) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, MBP(Thr232) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMBP Thr232
Specificity This antibody recognizes Thr229 in mice and Thr122 in rat, This is a highly specific antibody against MBP Thr232
ModificationPhosphorylation
Modification siteThr232
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range225-235/304
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Thr232
Gene ID number4155
Swiss ProtP02686
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, Induces T-cell proliferation, The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis, They have a role in both its formation and stabilization, and may also be involved in signaling pathways in T-cells and neural cells, maybe as components of transcriptional complexes, with each of them potentially having a specialized function, The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMBP(Thr232) Conjugated
Short name Conjugated, MBP(Thr232) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MBP(Thr232) (Antibody to)
Alternative techniqueantibodies
Identity 6925
Gene MBP
Long gene name myelin basic protein
Locus 18q23
Discovery year 1986-01-01
Entrez gene record 4155
Pubmed identfication 2425357
RefSeq identity NM_001025081
Havana BLAST/BLAT OTTHUMG00000132874

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