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MCAK Antibody

MCAK Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMCAK
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the MCAK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MCAK antibodyis to be used only for research purposes and not for diagnostics
Gene ID #11004
PurityAntigen affinity
Description It is mapped to 1p34, MCAK uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores, Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division, The protein encoded by this gene is a member of kinesin-like protein family, This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation, also called Mitotic centromere associated kinesin (MCAK), is a protein that in humans is encoded by the KIF2C gene, 1, Kinesin-like protein
ImmunogenHuman partial recombinant protein (AA 531-725) was used as the immunogen for this MCAK antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MCAK antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMCAK
Short nameMCAK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMCAK (Antibody to)
Alternative techniqueantibodies
Identity 6393
Gene KIF2C
Long gene name kinesin family member 2C
Synonyms gene KNSL6
Synonyms gene name kinesin-like 6 (mitotic centromere-associated kinesin)
Synonyms MCAK CT139
Locus 1p34, 1
Discovery year 1999-09-07
GenBank acession U63743
Entrez gene record 11004
Pubmed identfication 9434124
RefSeq identity NM_006845
Classification Kinesins
Havana BLAST/BLAT OTTHUMG00000008416

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