Name : MCKD2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9453899172
| Long name | MCKD2 Primary Polyclonal Antibody |
| Also known as | MCKD2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MCKD2/UMOD |
| Specificity | This is a highly specific antibody against MCKD2/UMOD |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 120-170/640 |
| Subcellular location | Cell membrane, Secreted |
| Source | KLH conjugated synthetic peptide derived from mouse MCKD2 |
| Gene ID number | 22242 |
| Swiss Prot | Q91X17 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Tamm-Horsfall urinary glycoprotein, Umod, Urehd1, Uromodulin, urehr4, THP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MCKD2 |
| Short name | MCKD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MCKD2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6942 |
| Gene | MCKD2 |
| Long gene name | medullary cystic kidney disease 2 (autosomal dominant) |
| Synonyms | ADMCKD2 |
| Locus | 16p12 |
| Discovery year | 1999-06-02 |
| Pubmed identfication | 10330352 |