Name : MCM4/CDC21 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5804206262
| Long name | MCM4/CDC21 Primary Polyclonal Antibody |
| Also known as | MCM4/CDC21 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MCM4/CDC21 |
| Specificity | This is a highly specific antibody against MCM4/CDC21 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MCM4 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Cleavage of MCM3, Expression of MCM proteins increases during cell growth, MCM proteins are regulated by E2F transcription factors, MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), The MCM proteins each contain an ATP-binding motif, and by protein kinases, are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle, including MCM2, peaking at G1 to S phase, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis, which can be prevented by caspase inhibitors, which induce MCM expression, which interact with MCM proteins to maintain the postreplicative state of the cell, which is predicted to mediate ATP-dependent opening of double-stranded DNA, The mini-chromosome maintenance (MCM) family of proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 19G antibody AI325074, 4, AU045576, CDC 21, CDC 54, CDC21 homolog, CDC54, DNA replication licensing factor MCM 4, DNA replication licensing factor MCM4, Homolog of S, KIAA4003, MCM 4, MCM 4 minichromosome maintenance deficient 4, MCM4, MCM4 minichromosome maintenance deficient 4, MCM4 minichromosome maintenance deficient 4, MCM4_HUMAN, MGC33310, Mcmd4, Minichromosome Maintenance 4, Minichromosome maintenance, Minichromosome maintenance complex component 4, Minichromosome maintenance deficient 4, Minichromosome maintenance deficient 4 homolog S, Minichromosome maintenance deficient S, P1 CDC21, P1-CDC21, P1CDC21, S, cerevisiae, cerevisiae, cerevisiae, cerevisiae 4, hCdc 21, hCdc21, homolog of, mKIAA4003, mcdc21, mitotin S, pombe cell devision cycle 21, CDC21 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MCM4/CDC21 |
| Short name | MCM4/CDC21 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MCM4/CDC21 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6947 |
| Gene | MCM4 |
| Long gene name | minichromosome maintenance complex component 4 |
| Synonyms gene | CDC21 |
| Synonyms gene name | MCM4 minichromosome maintenance deficient 4 (S, cerevisiae) |
| Synonyms | CDC54 hCdc21 P1-Cdc21 MGC33310 |
| Locus | 8q11, 21 |
| Discovery year | 1994-12-13 |
| Entrez gene record | 4173 |
| Pubmed identfication | 7601140 |
| RefSeq identity | NM_005914 |
| Classification | MCM family |
| Havana BLAST/BLAT | OTTHUMG00000164205 |