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MCM4/CDC21 Antibody

MCM4/CDC21 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameMCM4/CDC21 Primary Polyclonal Antibody
Also known asMCM4/CDC21 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMCM4/CDC21
SpecificityThis is a highly specific antibody against MCM4/CDC21
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MCM4
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cleavage of MCM3, Expression of MCM proteins increases during cell growth, MCM proteins are regulated by E2F transcription factors, MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), The MCM proteins each contain an ATP-binding motif, and by protein kinases, are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle, including MCM2, peaking at G1 to S phase, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis, which can be prevented by caspase inhibitors, which induce MCM expression, which interact with MCM proteins to maintain the postreplicative state of the cell, which is predicted to mediate ATP-dependent opening of double-stranded DNA, The mini-chromosome maintenance (MCM) family of proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 19G antibody AI325074, 4, AU045576, CDC 21, CDC 54, CDC21 homolog, CDC54, DNA replication licensing factor MCM 4, DNA replication licensing factor MCM4, Homolog of S, KIAA4003, MCM 4, MCM 4 minichromosome maintenance deficient 4, MCM4, MCM4 minichromosome maintenance deficient 4, MCM4 minichromosome maintenance deficient 4, MCM4_HUMAN, MGC33310, Mcmd4, Minichromosome Maintenance 4, Minichromosome maintenance, Minichromosome maintenance complex component 4, Minichromosome maintenance deficient 4, Minichromosome maintenance deficient 4 homolog S, Minichromosome maintenance deficient S, P1 CDC21, P1-CDC21, P1CDC21, S, cerevisiae, cerevisiae, cerevisiae, cerevisiae 4, hCdc 21, hCdc21, homolog of, mKIAA4003, mcdc21, mitotin S, pombe cell devision cycle 21, CDC21
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMCM4/CDC21
Short nameMCM4/CDC21 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMCM4/CDC21 (Antibody to)
Alternative techniqueantibodies
Identity 6947
Gene MCM4
Long gene name minichromosome maintenance complex component 4
Synonyms gene CDC21
Synonyms gene name MCM4 minichromosome maintenance deficient 4 (S, cerevisiae)
Synonyms CDC54 hCdc21 P1-Cdc21 MGC33310
Locus 8q11, 21
Discovery year 1994-12-13
Entrez gene record 4173
Pubmed identfication 7601140
RefSeq identity NM_005914
Classification MCM family
Havana BLAST/BLAT OTTHUMG00000164205

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