Name : MCM4/CDC21 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5561138503
| Long name | Cy5, 5 Conjugated, MCM4/CDC21 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MCM4/CDC21 |
| Specificity | This is a highly specific antibody against MCM4/CDC21 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human MCM4 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Cleavage of MCM3, Expression of MCM proteins increases during cell growth, MCM proteins are regulated by E2F transcription factors, MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), The MCM proteins each contain an ATP-binding motif, and by protein kinases, are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle, including MCM2, peaking at G1 to S phase, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis, which can be prevented by caspase inhibitors, which induce MCM expression, which interact with MCM proteins to maintain the postreplicative state of the cell, which is predicted to mediate ATP-dependent opening of double-stranded DNA, The mini-chromosome maintenance (MCM) family of proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | CDC54 hCdc21 P1-Cdc21 MGC33310 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | MCM4/CDC21 Conjugated |
| Short name | Conjugated, MCM4/CDC21 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, MCM4/CDC21 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6947 |
| Gene | MCM4 |
| Long gene name | minichromosome maintenance complex component 4 |
| Synonyms gene | CDC21 |
| Synonyms gene name | MCM4 minichromosome maintenance deficient 4 (S, cerevisiae) |
| Locus | 8q11, 21 |
| Discovery year | 1994-12-13 |
| Entrez gene record | 4173 |
| Pubmed identfication | 7601140 |
| RefSeq identity | NM_005914 |
| Classification | MCM family |
| Havana BLAST/BLAT | OTTHUMG00000164205 |