Name : MCM8 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN9485781515
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | MCM8 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the MCM8 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This MCM8 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9UJA3 |
| Purity | Antigen affinity |
| Description | 6 and 7, Alternatively spliced transcript variants encoding distinct isoforms have been described, The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins, This protein contains the central domain that is conserved among the MCM proteins, This protein has been shown to co-immunoprecipitate with MCM4, which suggests that it may interact with other MCM proteins and play a role in DNA replication, The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication |
| Immunogen | A portion of amino acids 322-350 from the human protein was used as the immunogen for this MCM8 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MCM8 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | MCM8 |
| Short name | MCM8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MCM8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16147 |
| Gene | MCM8 |
| Long gene name | minichromosome maintenance 8 homologous recombination repair factor |
| Synonyms gene | C20orf154 |
| Synonyms gene name | chromosome 20 open reading frame 154 minichromosome maintenance complex component 8 |
| Synonyms | MGC4816 MGC12866 MGC119522 MGC119523 dJ967N21, 5 REC |
| Synonyms name | REC homolog (Drosophila) |
| Locus | 20p12, 3 |
| Discovery year | 2001-07-17 |
| GenBank acession | AJ439063 |
| Entrez gene record | 84515 |
| Pubmed identfication | 12527764 |
| RefSeq identity | NM_032485 |
| Classification | MCM family |
| Havana BLAST/BLAT | OTTHUMG00000031822 |