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MDM4 ANTIBODY, ALEXA FLUOR 488

MDM4 ANTIBODY, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, MDM4 POLYCLONAL ANTIBODY
Also known asAnti-MDM4 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMDM4
SpecificityThis is a highly specific antibody against MDM4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range300-330/490
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MDM4
Gene ID Number4194
Swiss ProtO15151
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions, Inhibits degradation of MDM2, Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms MDMX HDMX
Properties Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MDM4 ANTIBODY, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMDM4
Short nameMDM4 ANTIBODY
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Mdm4 p53 binding protein homolog (mouse) (Antibody to)
Alternative to gene target BT, HDMX and MDMX and MRP1, MDM4 and IDBG-106054 and ENSG00000198625 and 4194, Mdm4 and IDBG-192393 and ENSMUSG00000054387 and 102641776, enzyme binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045023 and G0 to G1 transition and biological process this GO :0050821 and protein stabilization and biological process this GO :0071157 and negative regulation of cell cycle arrest and biological process this GO :0071456 and cellular response to hypoxia and biological process, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030330 and DNA damage response, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019899: enzyme binding, this GO :0008270: zinc ion binding, this GO :0019899: enzyme binding, 17248, 36413 and IDBG-628663 and ENSBTAG00000006255 and 100138492, 514225, Mdm4 p53 binding protein homolog (mouse)
Identity 6974
Gene MDM4
Long gene name MDM4, p53 regulator
Synonyms gene name human homolog of, mouse double minute 4, p53 binding protein (mouse) Mdm4 p53 binding protein homolog (mouse) , p53-binding protein Mdm4, transformed 3T3 cell double minute 4
Locus 1q32, 1
Discovery year 1997-09-05
GenBank acession AF007111
Entrez gene record 4194
Pubmed identfication 9226370 14660608
RefSeq identity NM_002393
Havana BLAST/BLAT OTTHUMG00000035877

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