Name : MEGF10 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2650032777
| Long name | FITC Conjugated, MEGF10 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MEGF10 |
| Specificity | This is a highly specific antibody against MEGF10 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human MEGF10 |
| Gene ID number | 84466 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | It is expressed at the cell surface in clusters around cell corpses during engulfment, MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain, MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern, The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1), The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup, which is an ortholog to CED-7, 140 amino acid protein encoded by the human gene MEGF10, MEGF10 is a 1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | KIAA1780 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MEGF10 Conjugated |
| Short name | FITC Conjugated, MEGF10 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, multiple epidermal growth factor-like-domains 10 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MEGF10 and IDBG-39569 and ENSG00000145794 and 84466, MEGF10 and IDBG-644881 and ENSBTAG00000000329 and 539136, Megf10 and IDBG-148090 and ENSMUSG00000024593 and 70417, Plasma membranes, protein binding, this GO :0001891 and pha this GO cytic cup and cellular component this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0014719 and satellite cell activation and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0014841 and satellite cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0042995 and cell projection and cellular component this GO :0043654 and recognition of apoptotic cell and biological process this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0051147 and regulation of muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, multiple EGF-like-domains 10 |
| Identity | 29634 |
| Gene | MEGF10 |
| Long gene name | multiple EGF like domains 10 |
| Synonyms gene name | multiple EGF-like-domains 10 |
| Locus | 5q23, 2 |
| Discovery year | 2006-03-31 |
| GenBank acession | AK021631 |
| Entrez gene record | 84466 |
| Pubmed identfication | 11347906 |
| RefSeq identity | NM_032446 |
| Classification | Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000128984 |