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Meis homeobox 3 Antibody, ALEXA FLUOR 488

Meis homeobox 3 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, Meis homeobox 3 Polyclonal Antibody
Also known asAnti-Meis homeobox 3 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMeis homeobox 3
SpecificityThis is a highly specific antibody against Meis homeobox 3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Meis homeobox 3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Mouse
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both Meis1 and Meis2 (also known as Meis-related gene 1 or Mrg1) are members of the TALE (â, Hox proteins are involved in regulating tissue patterning during development, In addition to binding with Hox proteins, In the pancreas, Like Hox and Pbx proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, Meis1 is implicated in oncogenesis, Meis2 and Meis3 (also designated Mrg1 and Mrg2, Meis2 preferentially associates with Pbx1, Pbx and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains, Pbx2 and Pbx3, Pdx1, The Hox proteins, Two Meis-related proteins, and are also expressed in lineage- and stage-specific patterns during adult hematopoietic differentiation and in leukemias, and these complexes contain distinct DNA-binding specificities, and together they associate with the pancreas-specific homeodomain factor, as it is overexpressed as a result of adjacent retroviral insertion in BHX-2 myeloid leukemias, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx- related Meis proteins, including Pbx1, possess largely similar sequence identity with Meis1 and are expressed in normal tissues and myeloid leukemias, respectively), to repress Pdx1-induced transcriptional activation, which include paralog groups 1-10, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site, &euro, &euro, &oelig, Hox, three amino acid loop extensionâ, ) family of homeodomain-containing proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Meis homeobox 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMeis homeobox 3
Short nameMeis homeobox 3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Meis homeobox 3 (Antibody to)
Alternative techniqueantibodies
Identity 17638
Gene MEIS3P2
Long gene name Meis homeobox 3 pseudogene 2
Synonyms gene name Meis1 homolog 3 (mouse) pseudogene 2
Locus 17p11, 2
Discovery year 2005-12-23
Entrez gene record 257468
RefSeq identity NG_002418
Classification TALE class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000059559

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