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MEK1/2(Ser218 + Ser222) Antibody

MEK1/2(Ser218 + Ser222) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMEK1/2(Ser218 + Ser222) Antibody
Also known asMEK1/2(Ser218 + Ser222) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMEK1/2 Ser218 + Ser222
Specificity These phosphorylation sites are homologous to Ser222 + Ser226 in MEK2 and are the same across the listed species, This is a highly specific antibody against MEK1/2 Ser218 + Ser222
Modification(s)Phosphorylation
Modification site(s)Ser218 + Ser222
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range180-230/393
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222
Gene ID number56045605
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As an essential component of MAP kinase signal transduction pathway, MAP kinases, This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals, act as an integration point for multiple biochemical signals, also known as extracellular signal-regulated kinases (ERKs), differentiation, this kinase is involved in many cellular processes such as proliferation, transcription regulation and development, which acts as a mitogen-activated protein (MAP) kinase kinase, The protein encoded by this gene is a member of the dual specificity protein kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Dual specicity mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAP kinase/Erk kinase 1, MAP/Erk kinase 1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, MEKK1, MKK 1, MKK1, Map2K1, Mitogen activated protein kinase kinase 1, PRKMK 1, PRKMK1, Protein kinase mitogen activated, Protein kinase mitogen activated kinase 1, kinase 1, MAP2K1phospho S218/S222, Protein kinase mitogen activated kinase 1 MAP kinase kinase 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK1/2(Ser218 + Ser222)
Short nameMEK1/2(Ser218 + Ser222) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMEK1/2(Ser218 and Ser222) (Antibody to)
Alternative techniqueantibodies
Identity 6840
Gene MAP2K1
Long gene name mitogen-activated protein kinase kinase 1
Synonyms gene PRKMK1
Synonyms MEK1 MAPKK1
Locus 15q22, 31
Discovery year 1993-11-05
GenBank acession L11284
Entrez gene record 5604
Pubmed identfication 9465908 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133196
Locus Specific Databases The Globin Gene Server LRG_725

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