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MEK1/2(Ser218 + Ser222) Antibody, FITC Conjugated

MEK1/2(Ser218 + Ser222) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, MEK1/2(Ser218 + Ser222) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMEK1/2 Ser218 + Ser222
Specificity These phosphorylation sites are homologous to Ser222 + Ser226 in MEK2 and are the same across the listed species, This is a highly specific antibody against MEK1/2 Ser218 + Ser222
ModificationPhosphorylation
Modification siteSer218 + Ser222
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range180-230/393
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222
Gene ID number56045605
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background As an essential component of MAP kinase signal transduction pathway, MAP kinases, This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals, act as an integration point for multiple biochemical signals, also known as extracellular signal-regulated kinases (ERKs), differentiation, this kinase is involved in many cellular processes such as proliferation, transcription regulation and development, which acts as a mitogen-activated protein (MAP) kinase kinase, The protein encoded by this gene is a member of the dual specificity protein kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms MEK1 MAPKK1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK1/2(Ser218 + Ser222) Conjugated
Short name FITC Conjugated, MEK1/2(Ser218 + Ser222) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MEK1/2(Ser218 and Ser222) (Antibody to)
Alternative techniqueantibodies
Identity 6840
Gene MAP2K1
Long gene name mitogen-activated protein kinase kinase 1
Synonyms gene PRKMK1
Locus 15q22, 31
Discovery year 1993-11-05
GenBank acession L11284
Entrez gene record 5604
Pubmed identfication 9465908 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133196
Locus Specific Databases The Globin Gene Server LRG_725

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