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MEK1 Antibody, Cy5.5 Conjugated

MEK1 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, MEK1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMEK1
SpecificityThis is a highly specific antibody against MEK1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range2-35/393
SourceKLH conjugated synthetic peptide derived from human MEK1
Gene ID number5604
Swiss ProtQ02750
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binding of extracellular ligands such as growth factors, Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, Depending on the cellular context, MAP2K1/MEK1 has been shown to export PPARG from the nucleus, One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2, The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, a nuclear receptor that promotes differentiation and apoptosis, adhesion, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, as well as in the fragmentation of the Golgi apparatus during mitosis, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), leading to their activation and further transduction of the signal within the MAPK/ERK cascade, metabolism and cytoskeletal rearrangements, predominantly through the regulation of transcription, survival and differentiation, this pathway mediates diverse biological functions such as cell growth, Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms MEK1 MAPKK1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetMEK1 Conjugated
Short name Conjugated, MEK1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, MEK1 (Antibody to)
Alternative techniqueantibodies
Identity 6840
Gene MAP2K1
Long gene name mitogen-activated protein kinase kinase 1
Synonyms gene PRKMK1
Locus 15q22, 31
Discovery year 1993-11-05
GenBank acession L11284
Entrez gene record 5604
Pubmed identfication 9465908 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133196
Locus Specific Databases The Globin Gene Server LRG_725

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