MEK1 Antibody, FITC Conjugated

MEK1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	FITC Conjugated, MEK1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Anti-FITC Antibody
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	MEK1
Specificity	This is a highly specific antibody against MEK1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	2-35/393
Source	KLH conjugated synthetic peptide derived from human MEK1
Gene ID number	5604
Swiss Prot	Q02750
Tested applications	IF(IHC-P)
Recommended dilutions	IF(IHC-P)(1:50-200)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Binding of extracellular ligands such as growth factors, Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, Depending on the cellular context, MAP2K1/MEK1 has been shown to export PPARG from the nucleus, One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2, The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, a nuclear receptor that promotes differentiation and apoptosis, adhesion, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, as well as in the fragmentation of the Golgi apparatus during mitosis, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), leading to their activation and further transduction of the signal within the MAPK/ERK cascade, metabolism and cytoskeletal rearrangements, predominantly through the regulation of transcription, survival and differentiation, this pathway mediates diverse biological functions such as cell growth, Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	494nm/518nm
Synonyms	MEK1 MAPKK1
Properties	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	MEK1 Conjugated
Short name	FITC Conjugated, MEK1 Antibody
Technique	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	FITC
Alternative name	fluorecein coupled, MEK1 (Antibody to)
Alternative technique	antibodies
Identity	6840
Gene	MAP2K1
Long gene name	mitogen-activated protein kinase kinase 1
Synonyms gene	PRKMK1
Locus	15q22, 31
Discovery year	1993-11-05
GenBank acession	L11284
Entrez gene record	5604
Pubmed identfication	9465908 8388392
Classification	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT	OTTHUMG00000133196
Locus Specific Databases	The Globin Gene Server LRG_725

MEK1 Antibody, FITC Conjugated

MEK1 Antibody, FITC Conjugated size: 0.1ml 333

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